TARA Skein platform

Skein develops an innovative Patient Data platform, supported by a EU-funded research and innovation grant.

Mobile apps

Personal data

UI/UX

The Challenge

In the realm of healthcare, the integration of patient-reported data into clinical practice and AI modelling presents complex challenges. Ethical data collection is paramount, requiring stringent adherence to patient privacy and consent, amidst diverse and often sensitive personal health information. Coherent data management is equally critical, demanding sophisticated systems that can process and store heterogeneous data efficiently while maintaining quality and interoperability with existing healthcare infrastructure. Further, translating this data into effective clinical support tools necessitates a user-friendly design that provides actionable insights for healthcare professionals, a task that must be balanced with the ethical development and deployment of AI models. These models, while promising for analysing vast datasets, face challenges in ensuring clinical relevance, accuracy, and the mitigation of inherent biases. Addressing these multifaceted challenges is essential for harnessing the full potential of patient-reported data in enhancing healthcare delivery and patient outcomes.

Among the clinical conditions, migraine represents one of the biggest opportunities for impact. Migraine is a chronic neurological disease that characterises by recurrent episodes of headache associated with nausea and sensitivity to light or sound. Migraines are very prevalent and affect 1 in 7 Europeans. They can be debilitating and costly, with an estimated cost of €125 billion in Europe each year due to lost productivity and healthcare. There are currently no cures for migraine and existing treatments provide only symptomatic relief.

The project

Our innovation

Skein is at the forefront of innovating healthcare technology, focusing on the development of sophisticated software solutions for health data management. This initiative encompasses a comprehensive suite of services, including the meticulous collection of health-related data, advanced analytical processes, and the extraction of actionable insights. Integral to this system is the provision of decision support, aimed at enhancing the efficacy and precision of healthcare delivery.

The platform

TARA Skein represents a pioneering, centralised platform designed to enhance decision-making and patient care. This platform systematically gathers, evaluates, and interprets extensive health data specific to individuals suffering from migraines. It integrates a multifaceted array of data sources, thereby enriching the insights garnered. These sources include detailed patient diaries, which chronicle triggers, attack patterns, and medication usage; patient-reported outcomes submitted via a specialised application; and quantitative data derived from wearable technology.

Furthermore, TARA Skein functions as a comprehensive health data repository, accessible to researchers. This access facilitates the discovery of nuanced patterns and insights into the intricate nature of migraine conditions. The ultimate objective is to refine and tailor treatment approaches, thereby augmenting the effectiveness of decision support systems in patient care. This innovative approach exemplifies the commitment to advancing healthcare through data-driven strategies, ensuring more personalised and effective treatment modalities for migraine sufferers.

Skein works together with patients and carers, as well as other healthcare professionals, to develop tools for delivering personalised treatments based on patient data collected via smartphone apps. This could help improve compliance with treatment plans by tailoring them according to each individual’s needs and circumstances.

Personalised medicine for migraine is based on the identification of early markers that indicate who, when and how will be affected by migraine. The researchers want to use biomarkers to identify a single or combination of factors that are suitable for early diagnosis, but also for the determination of the patient’s disease stage and progression.

Clinical trials

Currently the platform undergoes validation in clinical trials with leading healthcare partners in Europe.

Further information

TARA is funded by a €6mln EU grant that aims at developing data-driven personalised therapies and prevention strategies to control migraine attacks, while avoiding the side effects of presently available prophylactic drugs. This is the first time that a European project will bring together such a large group of stakeholders to address the challenges faced by people with migraine.

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